Phenobarbital is shown to shorten the half-life of doxycycline for so long as 2 months following barbiturate therapy is discontinued. This system is most likely in the induction of hepatic microsomal enzymes that metabolize the antibiotic.Barbiturates which includes pentobarbital are addictive and are already historically misused and abused illegal
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The use of barbiturates carries with it an involved possibility of psychological and/or Bodily dependence. The individual should be warned against growing the dose with the drug with out consulting a doctor.Barbiturates are usually not Typically the key drug of use for individuals who misuse them. In its place, barbiturates and benzodiazepines are